DxO Optics Pro 5.3 claims that "Aberrations are corrected by lens/camera specific modules, ensuring laboratory-grade precision without user intervention". While this sounds great on paper, when testing this with an image shot with a Canon EOS-1Ds Mark III, DxO was unable to remove the CA, neither with the default settings (i.e. no user intervention), nor with the maximum settings, despite using the lens/camera-specific DxO module for Canon EOS-1Ds Mark III with EF 16-35mm 1:2.8 L II USM lens.
It is hard to improve on the ACR result. Only the moiré was comparable to ACR (although on close inspection a bit more color moiré remains in the DxO result). The DxO CA results are vastly inferior to ACR and if you improve things in one area, other areas become totally unacceptable.